3 Win Nobel in Medicine for Gene Technology

This is kind of what I do in lab. A former co-worker actually got her Ph.D. in Mario Capecchi’s lab at Utah State. Pretty neat.

While I personally am not making a “knock-out” mouse as described in the article, my lab has done a lot of it, and I’m using several knock-outs in my thesis research. What I’m doing is actually adding back a gene to a knock-out mouse lacking that gene. To easier study what the protein produced from that gene does, when I add it back it contains a tag on it that will allow me to easily purify it from cells. It’s pretty cool stuff. Now, if only I could get it to work right…